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Talk About It


Talk About It


Editorial Reviews

Product Description

Nicole gives US powerful ballads on her new release that will readily be embraced, but Talk About It, is also a reflection of the musical versatility of the prolific energetic artists. [Note: This product is an authorized CD-R and is manufactured on demand]

Now this is world music--the kind of sound that defies classification and stretches itself beyond musical borders. Following up her multiple Dove Award-winning debut, Nicole C. Mullen is back with a vengeance on Talk About It. The energetic release carries a warm and joyous feel that unites rather than divides through its incorporation of pop, Ramp;B, hip-hop, and gospel. This melting-pot strategy complements Mullen's lyrical dedication to racial reconciliation. For example, on the rocking and rollicking "Black Light," Mullen sings about the need for integrity in today's leaders. She can also jam hard on such numbers as the release's title track, "Witness," and "Sometimes." Mullen changes speeds well on "Baby Girl" and "Let Me Go," paying musical homage to the likes of Stevie Wonder and Sly and the Family Stone. In fact, producer (and husband) David Mullen amply uses horns throughout, giving a slight wink to '60s soul. The ultimate result is a wonderful collage of stylish influences that will please music fans on repeated listens. --Michael Lyttle

Talk About It

September, 2021

No. 106 (9)

2020 Impact Factor: 9.941 Submission > Acceptance: 52 days

Long-term outcomes from the phase II L-MIND study of tafasitamab (MOR208) plus lenalidomide in patients with relapsed or refractory diffuse large B-cell lymphoma

This open-label, single-arm study investigated the long-term efficacy of tafasitamab plus lenalidomide in 81 patients with relapsed/refractory diffuse large B-cell lymphoma. The response rate was 57.5%, including complete responses in 40.0% of patients, and the median duration of response was 43.9 months. This treatment is a valuable option for patients not eligible for autologous stem-cell transplantation.

Johannes Duell et al.

Case Report

Clinical genomic profiling of novel grey zone lymphoma paired lesions with sequential central nervous system involvement in two adolescent patients

Grey zone lymphoma is a B-cell lymphoma, unclassifiable, with features intermediate between those of large B-cell lymphoma and classic Hodgkin lymphoma. The in-depth study of the two adolescent patients described in this case report expands the clinicopathological and genomic spectrum of this rare pediatric disease. Moreover, it provides information on their response to treatment.

Cagla Y. Benkli et al.


CAMT-MPL: congenital amegakaryocytic thrombocytopenia caused by MPL mutations - heterogeneity of a monogenic disorder - a comprehensive analysis of 56 patients

The clinical picture of 56 patients with congenital amegakaryocytic thrombocytopenia due to MPL mutations was much more varied than previously thought. Twenty-five per cent of them had no signs of thrombocytopenia at birth, and 50% had non-hematologic defects. Pancytopenia developed in (nearly) all patients and hematopoietic stem-cell transplantation was effective in 87% of cases.

Manuela Germeshausen et al.


Oxidative stress activates red cell adhesion to laminin in sickle cell disease

Sickle red blood cells exhibit abnormal adhesion to laminin mediated by Lu/BCAM protein at their surface. This study provides evidence of the involvement of oxidative stress in post-translational modifications of Lu/BCAM which impact the protein’s distribution and cis-interaction with glycophorin C at the cell surface activating its adhesive function in dense sickle red cells. The authors speculate that antioxidant drugs might attenuate this phenomenon.

Maria Alejandra Lizarralde-Iragorri et al.